In short Fertile Chip is an innovative selection method that enables the acquisition of sperm with the highest fertilization potential. It is particularly recommended for couples dealing with moderate to moderately advanced male factor infertility. Utilizing this procedure in an IVF program increases the chances of obtaining healthy embryos and achieving pregnancy.
Sperm is sorted using a special microfluidic device consisting of a chip with multiple channels and crypts.
Its purpose is to mimic the natural sperm selection processes that occur within the female body. This method also minimizes the harmful effects of sperm processing associated with centrifugation. The innovation of this technique lies in recreating the natural movement of sperm through the female reproductive tract, which the complex structure of the device is designed to imitate. During this 'journey,' weaker sperm are automatically eliminated—only those of the highest quality reach the final collection chamber and are subsequently used for fertilization. This serves as an alternative to the swim-up technique and density gradient selection methods.
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Fertile Chip is primarily recommended for couples struggling with infertility caused by male factors. It is particularly helpful in cases involving abnormalities related to:
It also allows for the selection of sperm based on DNA fragmentation. Sperm selection using this method is not performed in cases of extremely poor semen parameters, as the sperm would not be capable of navigating the microchannels to reach the collection chamber.
Sperm selected using Fertile Chip is characterized by:
As a result, the resulting embryos develop better, thereby increasing the chances of achieving pregnancy.
